• Adult weight change and premenopausal breast cancer risk: A prospective pooled analysis of data from 628,463 women 

      Schoemaker, Minouk J.; Nichols, Hazel B.; Wright, Lauren B.; Brook, Mark N.; Jones, Michael E.; O'Brien, Katie M.; Adami, Hans Olov; Baglietto, Laura; Bernstein, Leslie; Bertrand, Kimberly A.; Boutron-Ruault, Marie-Christine; Chen, Yu; Connor, Avonne E.; Dossus, Laure; Eliassen, A. Heather; Giles, Graham G; Gram, Inger Torhild; Hankinson, Susan E.; Kaaks, Rudolf; Key, Timothy J.; Kirsh, Victoria A.; Kitahara, Cari M.; Larsson, Susanna C.; Linet, Martha; Ma, Huiyan; Milne, Roger L.; Ozasa, Kotaro; Palmer, Julie R.; Riboli, Elio; Rohan, Thomas E.; Sacerdote, Carlotta; Sadakane, Atsuko; Sund, Malin; Tamimi, Rulla M.; Trichopoulou, Antonia; Ursin, Giske; Visvanathan, Kala; Weiderpass, Elisabete; Willett, Walter C.; Wolk, Alicja; Zeleniuch-Jacquotte, Anne; Sandler, Dale P.; Swerdlow, Anthony J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-03)
      Early‐adulthood body size is strongly inversely associated with risk of premenopausal breast cancer. It is unclear whether subsequent changes in weight affect risk. We pooled individual‐level data from 17 prospective studies to investigate the association of weight change with premenopausal breast cancer risk, considering strata of initial weight, timing of weight change, other breast cancer risk ...
    • Alcohol consumption, endogenous estrogen and mammographic density among premenopausal women 

      Frydenberg, Hanne; Flote, Vidar Gordon; Larsson, Ine Marie; Barrett, Emily S.; Furberg, Anne-Sofie; Ursin, Giske; Wilsgaard, Tom; Ellison, Peter; McTiernan, Anne; Hjartåker, Anette; Jasienska, Grazyna; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-07)
      Introduction: Alcohol consumption may promote aromatization of androgens to estrogens, which may partly explain the observations linking alcohol consumption to higher breast cancer risk. Whether alcohol consumption is associated with endogenous estrogen levels, and mammographic density phenotypes in premenopausal women remains unclear.<p> <p>Methods: Alcohol consumption was collected by self-report ...
    • Artificial Intelligence Evaluation of 122969 Mammography Examinations from a Population-based Screening Program 

      Larsen, Marthe; Aglen, Camilla Flåt; Lee, Christoph I.; Hoff, Solveig Roth; Lund-Hanssen, Håkon; Lång, Kristina; Nygård, Jan Franz; Ursin, Giske; Hofvind, Solveig Sand-Hanssen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-29)
      Background - Artificial intelligence (AI) has shown promising results for cancer detection with mammographic screening. However, evidence related to the use of AI in real screening settings remain sparse.<p> <p>Purpose - To compare the performance of a commercially available AI system with routine, independent double reading with consensus as performed in a population-based screening program. ...
    • Attendance to cervical cancer screening among Roma and non-Roma women living in North-Western region of Romania 

      Andreassen, Trude; Melnic, Adriana; Figueiredo, Rejane Augusta de Oliveira; Moen, Kåre; Şuteu, Ofelia; Nicula, Florian; Ursin, Giske; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-27)
      <p><i>Objectives</i>: Romania has Europe’s highest incidence and mortality rates of cervical cancer. Participation in the national cervical cancer-screening programme is low, especially among minority Roma women.</p> <p><i>Methods</i>: We conducted a cross-sectional study, using a structured questionnaire aiming to quantify reasons for screening attendance among women in North-Western region of ...
    • Breast cancer risk after recent childbirth: A pooled analysis of 15 prospective studies 

      Nichols, Hazel B.; Schoemaker, Minouk J.; Cai, Jianwen; Xu, Jiawei; Wright, Lauren B.; Brook, Mark N.; Jones, Michael E.; Adami, Hans Olov; Baglietto, Laura; Bertrand, Kimberly A.; Blot, William J.; Boutron-Ruault, Marie-Christine; Dorronsoro, Miren; Dossus, Laure; Eliassen, A. Heather; Giles, Graham G.; Gram, Inger Torhild; Hankinson, Susan E.; Hoffman-Bolton, Judy; Kaaks, Rudolf; Key, Timothy J.; Kitahara, Cari M.; Larsson, Susanna C.; Linet, Martha; Merritt, Melissa A.; Milne, Roger L.; Pala, Valeria; Palmer, Julie R.; Peeters, Petra H.; Riboli, Elio; Sund, Malin; Tamimi, Rulla M.; Tjønneland, Anne; Trichopoulou, Antonia; Ursin, Giske; Vatten, Lars Johan; Visvanathan, Kala; Weiderpass, Elisabete; Wolk, Alicja; Zheng, Wei; Weinberg, Clarice R.; Swerdlow, Anthony J.; Sandler, Dale P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-01)
      <i>Background</i>: Parity is widely recognized as protective for breast cancer, but breast cancer risk may be increased shortly after childbirth. Whether this risk varies with breastfeeding, family history of breast cancer, or specific tumor subtype has rarely been evaluated.<p> <p><i>Objective</i>: To characterize breast cancer risk in relation to recent childbirth.<p> <p>Design</i> : Pooled ...
    • Controversies about cervical cancer screening: A qualitative study of Roma women's (non)participation in cervical cancer screening in Romania 

      Andreassen, Trude; Weiderpass, Elisabete; Nicula, Florian; Suteu, Ofelia; Itu, Andreea; Bumbu, Minodora; Tincu, Aida; Ursin, Giske; Moen, Kåre (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-26)
      Romania has Europe's highest incidence and mortality of cervical cancer. While a free national cervical cancer-screening programme has been in operation since 2012, participation in the programme is low, particularly in minority populations. The aim of this study was to explore Roma women's (non)participation in the programme from women's own perspectives and those of healthcare providers and policy ...
    • Different measures of smoking exposure and mammographic density in postmenopausal Norwegian women : a cross-sectional study 

      Bremnes, Yngve; Bjurstam, Nils; Ursin, Giske; Gram, Inger Torhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2007-10-26)
      Background: Recent cohort studies have suggested an increased risk of breast cancer with long duration of smoking, and with smoking initiation before first birth. Cigarette smoking may have both carcinogenic effects and antiestrogenic effects on the breast tissue. We decided to examine the relationship between different measures of smoking exposure and mammographic density. Methods: Lifetime ...
    • Ethnic differences in the incidence of cancer in Norway 

      Vik, Kirsti Lund; Qureshi, Samera Azeem; Møller, Bjørn; Weiderpass, Elisabete; Deapen, Dennis; Kumar, Bernadette. N; Ursin, Giske (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-24)
      Traditionally there have been differences in cancer incidence across geographic regions. When immigrants have moved from low-income to high-income countries, their incidence have changed as they have adapted to the lifestyle in the new host country. Given worldwide changes in lifestyle factors over time, we decided to examine cancer incidence in immigrant groups in Norway, a country with a recent ...
    • Gene variations in oestrogen pathways, CYP19A1 , daily 17ß-estradiol and mammographic density phenotypes in premenopausal women. 

      Flote, Vidar Gordon; Furberg, Anne-Sofie; McTiernan, Anne; Frydenberg, Hanne; Ursin, Giske; Iversen, Anita; Lofterød, Trygve; Ellison, Peter T.; Wist, Erik; Egeland, Thore; Wilsgaard, Tom; Makar, Karen W; Chang-Claude, Jenny; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-12-19)
    • Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density 

      Gram, Inger Torhild; Biong, M; Brill, I; Bremnes, Yngve; Johansen, F; Solvang, Hiroko Kato; Alnaes, GIG; Fagerheim, Toril; Chanock, Stephen; Burdett, L; Yeager, M; Ursin, Giske; Kristensen, Vessela N. (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
    • Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer 

      Couch, Fergus J.; Kuchenbaecker, Karoline B.; Michailidou, Kyriaki; Mendoza-Fandino, Gustavo A.; Nord, Silje; Lilyquist, Janna; Olswold, Curtis; Hallberg, Emily; Agata, Simona; Ahsan, Habibul; Aittomäki, Kristiina; Ambrosone, Christine; Andrulis, Irene L.; Anton-Culver, Hoda; Arndt, Volker; Arun, Banu K.; Arver, Brita; Barile, Monica; Barkardottir, Rosa; Barrowdale, Daniel; Beckmann, Lars; Beckmann, Matthias W.; Benitez, Javier; Blank, Stephanie V.; Blomqvist, Carl; Bogdanova, Natalia V.; Bojesen, Stig E.; Bolla, Manjeet K.; Bonanni, Bernardo; Brauch, Hiltrud; Brenner, Hermann; Burwinkel, Barbara; Buys, Saundra S.; Caldes, Trinidad; Caligo, Maria A.; Canzian, Federico; Carpenter, Jane; Chang-Claude, Jenny; Chanock, Stephen J.; Chung, Wendy K.; Claes, Kathleen B.M.; Cox, Angela; Cross, Simon S.; Cunningham, Julie M.; Czene, Kamila; Daly, Mary B.; Damiola, Francesca; Darabi, Hatef; De La Hoya, Miguel; Devilee, Peter; Diez, Orland; Ding, Yuan C.; Dolcetti, Riccardo; Domchek, Susan M.; Dorfling, Cecilia M.; Dos-Santos-Silva, Isabel; Dumont, Martine; Dunning, Alison M; Eccles, Diana M; Ehrencrona, Hans; Ekici, Arif B; Eliassen, Heather; Ellis, Steve; Fasching, Peter A; Figueroa, Jonine; Flesch-Janys, Dieter; Försti, Asta; Fostira, Florentia; Foulkes, William D; Friebel, Tara; Friedman, Eitan; Frost, Debra; Gabrielson, Marike; Gammon, Marilie D; Ganz, Patricia A; Gapstur, Susan M; Garber, Judy; Gaudet, Mia M; Gayther, Simon A; Gerdes, Anne-Marie; Ghoussaini, Maya; Giles, Graham G; Glendon, Gord; Godwin, Andrew K; Goldberg, Mark S; Goldgar, David E; Gonzalez-Neira, Anna; Greene, Mark H; Gronwald, Jacek; Guenel, Pascal; Gunter, Marc; Haeberle, Lothar; Haiman, Christopher A; Hamann, Ute; Hansen, Thomas V O; Hart, Steven; Healey, Sue; Heikkinen, Tuomas; Henderson, Brian E; Herzog, Josef; Hogervorst, Frans B L; Hollestelle, Antoinette; Hooning, Maartje J; Hoover, Robert N; Hopper, John L; Humphreys, Keith; Hunter, David J; Huzarski, Tomasz; Imyanitov, Evgeny N; Isaacs, Claudine; Jakubowska, Anna; James, Paul; Janavicius, Ramunas; Jensen, Uffe Birk; John, Esther M; Jones, Michael; Kabisch, Maria; Kar, Siddhartha; Karlan, Beth Y; Khan, Sofia; Khaw, Kay-Tee; Kibriya, Muhammad G; Knight, Julia A; Ko, Yon-Dschun; Konstantopoulou, Irene; Kosma, Veli-Matti; Kristensen, Vessela N.; Kwong, Ava; Laitman, Yael; Lambrechts, Diether; Lazaro, Conxi; Lee, Eunjung; Le Marchand, Loic; Lester, Jenny; Lindblom, Annika; Lindor, Noralane; Lindstrom, Sara; Liu, Jianjun; Long, Jirong; Lubinski, Jan; Mai, Phuong L; Makalic, Enes; Malone, Kathleen E; Mannermaa, Arto; Manoukian, Siranoush; Margolin, Sara; Marme, Frederik; Martens, John W M; Mcguffog, Lesley; Meindl, Alfons; Miller, Austin; Milne, Roger L; Miron, Penelope; Montagna, Marco; Mazoyer, Sylvie; Mulligan, Anna M; Muranen, Taru A; Nathanson, Katherine L; Neuhausen, Susan L; Nevanlinna, Heli; Nordestgaard, Børge G; Nussbaum, Robert L; Offit, Kenneth; Olah, Edith; Olopade, Olufunmilayo I; Olson, Janet E; Osorio, Ana; Park, Sue K; Peeters, Petra H; Peissel, Bernard; Peterlongo, Paolo; Peto, Julian; Phelan, Catherine M; Pilarski, Robert; Poppe, Bruce; Pylkäs, Katri; Radice, Paolo; Rahman, Nazneen; Rantala, Johanna; Rappaport, Christine; Rennert, Gad; Richardson, Andrea; Robson, Mark; Romieu, Isabelle; Rudolph, Anja; Rutgers, Emiel J; Sanchez, Maria-Jose; Santella, Regina M; Sawyer, Elinor J; Schmidt, Daniel F; Schmidt, Marjanka K; Schmutzler, Rita K; Schumacher, Fredrick; Scott, Rodney; Senter, Leigha; Sharma, Priyanka; Simard, Jacques; Singer, Christian F; Sinilnikova, Olga M; Soucy, Penny; Southey, Melissa; Steinemann, Doris; Stenmark-Askmalm, Marie; Stoppa-Lyonnet, Dominique; Swerdlow, Anthony; Szabo, Csilla I; Tamimi, Rulla; Tapper, William; Teixeira, Manuel R; Teo, Soo-Hwang; Terry, Mary B; Thomassen, Mads; Thompson, Deborah; Tihomirova, Laima; Toland, Amanda E; Tollenaar, Robert A E M; Tomlinson, Ian; Truong, Thérèse; Tsimiklis, Helen; Teulé, Alex; Tumino, Rosario; Tung, Nadine; Turnbull, Clare; Ursin, Giske; Van Deurzen, Carolien H M; Van Rensburg, Elizabeth J; Varon-Mateeva, Raymonda; Wang, Zhaoming; Wang-Gohrke, Shan; Weiderpass, Elisabete; Weitzel, Jeffrey N; Whittemore, Alice; Wildiers, Hans; Winqvist, Robert; Yang, Xiaohong R; Yannoukakos, Drakoulis; Yao, Song; Zamora, M Pilar; Zheng, Wei; Hall, Per; Kraft, Peter; Vachon, Celine; Slager, Susan; Chenevix-Trench, Georgia; Pharoah, Paul D P; Monteiro, Alvaro A N; Garcia-Closas, Montserrat; Easton, Douglas F; Antoniou, Antonis C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-27)
      Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P<5 × 10−8) with oestrogen receptor (ER)-negative breast cancer and BRCA1-associated breast cancer risk. In this study, to identify new ER-negative susceptibility loci, we performed a meta-analysis of 11 genome-wide association studies (GWAS) consisting of 4,939 ER-negative ...
    • Identification of potential carcinogenic and chemopreventive effects of prescription drugs: A protocol for a Norwegian registry-based study 

      Kulle, Bettina; Støer, Nathalie Charlotte; Martinsen, Jan Ivar; Ursin, Giske; Weiderpass, Elisabete; Thoresen, G. Hege; Debernard, Karen A. Boldingh; Karlstad, Øystein; Pottegard, Anton; Friis, Søren (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-08)
      <i>Introduction</i> - Surveillance of unintended effects of pharmaceuticals (pharmacovigilance or drug safety) is crucial, as knowledge of rare or late side effects is limited at the time of the introduction of new medications into the market. Side effects of drugs may involve increased or decreased risk of cancer, but these typically appear after a long induction period. This fact, together with ...
    • Low-dose aspirin and risk of breast cancer: a Norwegian population-based cohort study of one million women 

      Løfling, Lukas; Støer, Nathalie Charlotte; Nafisi, Sara; Ursin, Giske; Hofvind, Solveig Sand-Hanssen; Botteri, Edoardo (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-06)
      Several studies evaluated the association between aspirin use and risk of breast cancer (BC), with inconsistent results. We identifed women aged≥50 years residing in Norway between 2004 and 2018, and linked data from nationwide registries; including the Cancer Registry of Norway, the Norwegian Prescription Database, and national health surveys. We used Cox regression models to estimate the ...
    • Mediterranean Dietary Pattern and Risk of Breast Cancer 

      Couto, Elisabeth; Sandin, Sven; Löf, Marie; Ursin, Giske; Adami, Hans-Olof; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: A Mediterranean diet has a recognized beneficial effect on health and longevity, with a protective influence on several cancers. However, its association with breast cancer risk remains unclear. Objective: We aimed to investigate whether adherence to a Mediterranean dietary pattern influences breast cancer risk. Design: The Swedish Women’s Lifestyle and Health cohort study includes ...
    • Menopausal hormone therapy and breast cancer risk: effect modification by body mass through life 

      Sandvei, Marie Søfteland; Vatten, Lars Johan; Bjelland, Elisabeth Krefting; Eskild, Anne; Hofvind, Solveig; Ursin, Giske; Opdahl, Signe (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-06)
      It is not known whether increased breast cancer risk caused by menopausal hormone therapy (HT) depends on body mass patterns through life. In a prospective study of 483,241 Norwegian women aged 50–69 years at baseline, 7656 women developed breast cancer during follow-up (2006–2013). We combined baseline information on recalled body mass in childhood/adolescence and current (baseline) body mass index ...
    • Menopausal hormone therapy and colorectal cancer: a linkage between nationwide registries in Norway. 

      Botteri, Edoardo; Støer, Nathalie Charlotte; Sakshaug, Solveig; Graff-Iversen, Sidsel; Vangen, Siri; Hofvind, Solveig; de Lange, Thomas; Bagnardi, Vincenzo; Ursin, Giske; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-15)
      Objectives: <br> With the present study, we aimed to investigate the association between menopausal hormone therapy (HT) and risk of colorectal cancer (CRC). <br> Setting: <br> Cohort study based on the linkage of Norwegian population-based registries. <br> Participants: <br> We selected 466822 Norwegian women, aged 55–79, alive and residing in Norway as of 1 January 2004, and we followed ...
    • Menopausal hormone therapy and risk of melanoma: Do estrogens and progestins have a different role? 

      Botteri, Edoardo; Støer, Nathalie; Sakshaug, Solveig; Graff-Iversen, Sidsel; Vangen, Siri; Hofvind, Solveig; Ursin, Giske; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-07)
      The association between use of menopausal hormone therapy (HT) and occurrence of skin malignant melanoma (SMM) is controversial. We investigated the issue in a nationwide cohort of 684,696 Norwegian women, aged 45–79 years, followed from 2004 to 2008. The study was based on linkage between Norwegian population registries. Multivariable Poisson regression models were used to estimate the effect of ...
    • Overdiagnosis – exemplified with mammographic screening 

      Hofvind, Solveig Sand-Hanssen; Mangerud, Gunhild; Holen, åsne Sørlien; Ursin, Giske (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-12)
      Hovedmålsettingen med organisert mammografiscreening er å oppdage brystkreft i et tidlig stadium og dermed redusere sykelighet og dødelighet av sykdommen. En ulempe er overdiagnostikk. Verdens helseorganisasjons kreftforskningsinstitutt definerer overdiagnostikk i mammografiscreening som brystkreft som ikke ville blitt diagnostisert i kvinnens levetid dersom hun ikke hadde deltatt i screening. Vi ...
    • Percentage density, Wolfe's and Tabár's mammographic patterns. Agreement and association with risk factors for breast cancer 

      Gram, Inger Torhild; Ursin, Giske; Maskarinec, Gertraud; Bremnes, Yngve; Bjurstam, Nils; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2005-08-25)
      Introduction: The purpose of this report was to classify mammograms according to four methods and to examine their agreement and their relationship to selected risk factors for breast cancer. Method: Mammograms and epidemiological data were collected from 987 women, aged 55 to 71 years, attending the Norwegian Breast Cancer Screening Program. Two readers each classified the mammograms according ...
    • Plasma levels of leptin and mammographic density among postmenopausal women. A cross-sectional study 

      Stuedal, Anne; Bremnes, Yngve; Gram, Inger Torhild; Ursin, Giske; Veierød, Marit B.; Reseland, Janne E.; Drevon, Christian A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-09-29)
      Introduction Obesity has been linked to increased risk of breast cancer in postmenopausal women. Increased peripheral production of estrogens has been regarded as the main cause for this association, but other features of increased body fat mass may also play a part. Leptin is a protein produced mainly by adipose tissue and may represent a growth factor in cancer. We examined the association ...